HEALTHSPAN

Healthspan is more important than lifespan, so why don’t more people know about it?

HEALTHSPAN is the period of life spent in good health, free from the chronic diseases and disabilities of aging. This definition implies that healthspan is a length of chronological time beginning at birth and ending at some subsequent time when an individual is no longer in good health and/or is suffering from diseases or disabilities of aging (Kaeberlein, 2018).

However, being “healthy” means different things to different people. A better definition might include being free from serious disease. A disease is considered to be serious if it is a leading cause of death.

A Newborn today has an extremely good chance of living to 100 and beyond. To cope, we need an economic, cultural and medical Transformation aimed at changing how we age while treating Health lifelong by Lifecare.

The integrated perspective of THE HEALTH CAPTAINS INSTITUTE is built on three interconnected pillars:

Healthspan Medicine (Healthy Longevity Medicine) focuses on applying the biology of ageing in clinical settings to enable prevention and personalized care. Healthspan Science (Healthy Longevity Science) provides the essential understanding of biological, social, and environmental influences on ageing, guiding research and intervention.

The Healthspan Economy supports the translation and scaling of these innovations by developing sustainable value chains and policy frameworks that promote long-term health and vitality.

Together, these areas form a comprehensive longevity strategy that connects scientific discovery, medical application, and economic sustainability—advancing a future where more people live longer in good health.

Healthspan Medicine = Healthy Longevity Medicine

Definition:
Healthspan Medicine and / or Healthy Longevity Medicine is an emerging medical discipline focused on extending the period of life spent in good health by targeting the biological mechanisms of ageing itself, rather than merely treating individual age-related diseases. It emphasizes early prevention, resilience, and system-wide interventions.

Key characteristics:

  • Uses biological age markers (e.g., omics data, digital health signals) instead of relying solely on chronological age.

  • Applies geroprotective therapies, repurposed drugs, and interventions such as nutritional modulation, physical activity, and cellular rejuvenation.

  • Relies on integration of personalized, predictive, and preventive approaches (P4 medicine).

  • Seeks to transform healthcare systems from reactive disease care to proactive health maintenance across the lifespan.

THE 5 PILLARS OF HEALTHY LONGEVITY

Overview of the key pillars for sustainable Healthy Longevity, all with positive impact on the expansion of the Healthspan to decrease the Sickspan by THE HEALTH CAPTAINS CLUB:

  1. Healthy Exercise empowered by being your own Health Captain
  2. Healthy Nutrition empowered by being your own Health Captain
  3. Healthy Sleep empowered by being your own Health Captain
  4. Healthy Mindset: 360º Brain Health: Mental, Emotional and Social Healthy Longevity empowered by THE HEALTH CAPTAINS CLUB Grand Salons for Healthy Longevity to scale meaningful Togetherness to positively inspire your 100 Billion Braincells by Input out of Music, Art, Medicine, Science, Philosophy, Literature, History, Entrepreneurship, Innovation and new Technologies as Source of sustainable SYNAPTING of your about 10.000 Synapsis of each of your about 100 Billion Braincells.
  5. Healthy Longevity Medicine empowered by molecular Hallmarks of Aging, Biological Clock and Precision Health Diagnostics to optimize individually the Healthy Longevity Pillars 1.-4. and to tailor additional Precision Health Interventions to the Individual “n-of-1” in Healthy Longevity Medical Centers powered by Academic Medical Centers with the Result in the coming years and decades to expand the Healthspan about 10 to 20 to even 30 more Years – reflect on and prepare the Purpose of your Life after the Age of 60-70 Years up to 100 Healthy Years:

“First be your own Health Captain, for your Family, for your Friends, for your Colleagues, for your Employees in your Community as a Role Model for Healthy Longevity” – welcome on Board as a Member of THE HEALTH CAPTAINS CLUB for more access towards Healthy Longevity Knowledge and Healthy Longevity Communities – more @ https://healthcaptains.club :

The fundament for Healthy Longevity seems to be long term healthy social relationships as the „Harvard Study of Adult Development“, which started over 80 years ago, describes loneliness as one of the most powerful killers and „The people who were the most satisfied in their relationships at age 50 were the healthiest at age 80.”

Holistic Brain Health should be the basic key towards Healthy Longevity to give the other pillars more substance and effective power to expand the healthspan.

By the Definition of Healthy Longevity Medicine Society “Healthy Longevity Medicine is optimizing healthspan by targeting ageing processes across the lifespan“. Healthy Longevity at scale needs therefore the self-navigation of Exercise, Nutrition, Sleep and 360º Brain Health. All these pillars needs more basic science and direct knowledge transfer towards the medical communities and societies at the same level:

„The Health Captain will be the CEO of his own Health by navigating his Healthy Longevity with his fingertips on his smartphone to expand his individual Healthspan over Lifetime“

BOOKLIST

HealthyLongevity starts with HealthyLongevityKnowledge

More on Linkedin @ THE HEALTH CAPTAINS INSTITUTE

LEADERS are READERS.

1. Exercise

  • Outlive: The Science and Art of Longevity
    Peter Attia, MD & Bill Gifford (2023) – ISBN-13: 978-0593236598 – Focuses on medical prevention (“Medicine 3.0”), lifestyle, and personalized strategies to maximize healthspan—covering exercise, nutrition, early diagnostics, and metabolic health. A New York Times bestseller and widely regarded clinical reference.

  • Age Later: Health Span, Life Span, and the New Science of LongevityNir Barzilai & Sean Pratt (2020)
    ISBN‑13: 978‑1250752581

2. Nutrition

  • The Longevity Diet
    Valter Longo, PhD (2018) – ISBN-13: 978-1405933940 – Based on decades of research, this book introduces fasting-mimicking diets, Blue Zone principles, and plant-based eating as core components of a scientifically grounded approach to prolonging healthspan.

  • The Healthspan Solution: How and What to Eat to Add Life to Your YearsRaymond Cronise & Julieanna Hever (2017)
    ISBN‑13: 978‑1465490070

  • Radical LongevityAnn Louise Gittleman (2021)
    ISBN‑13: 978‑0738286150

3. Sleep

  • Why We Die: The New Science of Aging and the Quest for ImmortalityVenki Ramakrishnan (2024)
    ISBN‑13: TBD (recent release); Nobel Laureate insights on essentials like sleeping 8 hours 

4. 360º Brain Health

  • The Longevity Book: The Biology of Resilience, the Privilege of Time and the New Science of AgeCameron Diaz & Sandra Bark (2017)
    ISBN‑13: 978‑0008139612

  • Survival of the SickestSharon Moalem & Jonathan Prince (2007)
    ISBN‑10: 0‑06‑088965‑9

  • Epigenetics and Human Longevity: A Short IntroductionHealthSpan Institute (2023)
    ISBN‑13: 979‑8866070077

5. Healthy Longevity Medicine 

  • Lifespan: Why We Age—and Why We Don’t Have To
    David Sinclair, PhD & Matthew LaPlante (2019) – ISBN-13: 978-1501191978 – Harvard geneticist David Sinclair explores molecular mechanisms of aging, including sirtuins, NAD+ metabolism, and epigenetic reprogramming, with the provocative thesis that aging is a treatable condition.
  • Ending Aging: The Rejuvenation Breakthroughs that Could Reverse Human Aging in Our LifetimeAubrey de Grey & Michael Rae (2007)
    ISBN‑13: 978‑0312367060
  • The Healthspan Code: How to Reverse Biological AgeProf. Camillo Ricordi (2022)
    ISBN‑13: 979‑8365484078
  • Super Agers: An Evidence-Based Approach to Longevity
    Eric Topol (2025) – ISBN-13: 978-1668067666 – A forthcoming volume from a digital health pioneer that explores how AI, precision diagnostics, wearables, and genomics can support lifelong vitality, independence, and cognitive resilience.
  • Young Forever: The Secrets to Living Your Longest, Healthiest Life
    Mark Hyman, MD (2023) – ISBN-13: 978-0593230800 – A functional medicine framework for healthy aging focusing on detoxification, metabolic repair, food-as-medicine, inflammation control, and the integration of emotional health and purpose.
  • Radical Longevity
    Ann Louise Gittleman, PhD (2021) – ISBN-13: 978-0738286150 – Provides an integrative nutrition and lifestyle approach to aging, emphasizing toxin elimination, mitochondrial support, hormone balancing, and cognitive protection.
  • The Age of Scientific Wellness: Why the Future of Medicine Is Personalized, Predictive, Data-Rich, and Precise
    Leroy Hood, PhD & Nathan Price, PhD (2023) – ISBN-13: 978-0670098614 – Describes how systems biology, multi-omics, and artificial intelligence are transforming healthcare from reactive to proactive. Presents a vision for precision longevity medicine based on deep individual data.

Healthspan Economy & Systems-Level Vision

  • The Longevity Economy: Unlocking the World’s Fastest‑Growing, Most Misunderstood MarketJoseph F. Coughlin (2017)
    ISBN‑13: 978‑1610396639

  • The Longevity Imperative: How to Build a Healthier and More Productive Society to Support Our Longer LivesAndrew J. Scott (2024)
    ISBN‑13: 978‑1541604506

  • Longevity GuidebookPeter H. Diamandis (2025)
    ISBN‑13: 978‑1636804279

Bonus Nobel Laureate Books

  • Why We Die: The New Science of Ageing and the Quest for Immortality
    Venki Ramakrishnan (2024) – Nobel Laureate in Chemistry (2009) for ribosome structure
    ISBN‑13: 978‑1529369250 – Delivers a profound and balanced exploration of aging biology and the role of lifestyle in healthspan. Ramakrishnan examines cellular mechanisms—such as senescence, DNA damage, and mitochondrial decline—while cautioning against overhyped “immortality” claims. Instead, he reinforces that proven strategies like good sleep, nutritious diet, exercise, social connection, and routine medical care remain the most reliable path to longevity

  • The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer
    Elizabeth Blackburn (Nobel Laureate) & Elissa Epel (2017) – ISBN-13: 978-1455508345 – An evidence-based guide to how telomere length—impacted by stress, sleep, nutrition, and social connection—can influence aging and disease risk. Written by a Nobel laureate who co-discovered telomerase.

Healthspan Medicine & Science

Definition:
Healthspan Medicine & Science is the interdisciplinary field that investigates the determinants, mechanisms, and modifiers of healthy ageing. It integrates molecular biology, systems medicine, public health, digital technologies, and social sciences to understand and influence how long individuals live in good health.

Core areas:

  • Studies the Hallmarks of Ageing, genomic stability, cellular senescence, and other longevity pathways.

  • Combines multi-omics, AI-driven analytics, and longitudinal Health Data to identify predictors and modifiers of healthspan.

  • Examines the role of environmental exposures (exposome), social determinants, and behavioral factors in ageing.

  • Encourages systems-based research collaborations and translational frameworks to move discoveries into practice.

Global Conferences Driving Healthspan Innovation

YOUR INPUT IS WELCOME

Global Healthspan Summit – Hevolution Foundation

Location: Riyadh, Saudi Arabia (Global Rotation)
Chairman & CEO: Dr. Mehmood Khan
Focus: Healthspan economy, science funding, longevity investment models.
Homepage: https://www.ghs2025.com

Longevity Med Summit

Location: Lisbon, Portugal
Focus: Clinical and biotech translation, diagnostics, precision health, and public healthspan strategies.
Homepage: https://longevitymedsummit.com

Genii Longevity Conference

Location: Geneva, Switzerland
Focus: Longevity capital, regulatory harmonization, global innovation networks.
Homepage: https://geniilongevity.com

Healthspan Summit

Location: Los Angeles, USA
Focus: Clinical longevity medicine, technology integration, investment panels.
Homepage: https://www.hssummit.com

Longevity Leadership Conference

Location: Playa Vista, California
Focus: Strategic business development and leadership in the healthspan innovation space.
Homepage: https://www.healthspanevents.com/longevityleadershipconference

HEAT Congress / Blue Zone Wellness Summit

Location: Bangkok, Thailand
Focus: Peptides, mitochondria, AI wellness, circadian health, and Asia-Pacific ecosystem.
Homepage: https://heatantiaging.com

Aging Research & Drug Discovery (ARDD)

Location: Copenhagen & New York (Hybrid)
Focus: Molecular and translational aging biology, biomarkers, therapeutics, and diagnostics.
Homepage: https://www.agingpharma.org

Targeting Healthy Longevity Webinar Series

Location: Virtual – Organized by NUS Centre for Healthy Longevity
Leads: Prof. Brian K. Kennedy, Prof. Andrea B. Maier
Homepage: https://www.healthy-longevity.org

GIANT Health – Longevity Track

Location: London, UK
Focus: AI, biotech, epigenetics, and commercializing regenerative health innovations.
Homepage: https://www.giant.health/healthspan–longevity

HEALTH CAPTAINS HEALTHY LONGEVITY ISLAND SUMMIT Föhr-Amrum-Sylt

Location: North Frisian Islands, Germany (Annual: Starting on Ascension Day as The Health Captains Think Tank since 2003)
Focus: Interdisciplinary leadership summits bridging medicine, science, innovation, policy, and investment for Healthy Longevity and transformation of healthcare from SickCare towards LifeCare: From imprecision disease-reactive Healthcare towards the SUPERCONVERGENCE of 1. Sustainable value-based Healthcare 2. Healthy Longevity Healthspan Optimization  Medicine 3. Blue Zone Community Care 4. One Health Lifecare – “From Island-centered towards World-centered – Healthy Longevity Medicine on Islands as an sustainable Role and Inspiration Model for the World.
Homepage: https://www.healthcaptains.club/events/foehr-amrum-sylt/

Leading International Institutions Advancing Healthspan Science

Buck Institute for Research on Aging
Location: Novato, California, USA
President & CEO: Dr. Eric Verdin
Focus: Translational and basic biomedical research in aging.
Key Themes: Geroscience, inflammation, cellular senescence, AI diagnostics, therapeutics.
Homepage: https://buckinstitute.org

Salk Institute – Healthy Aging Initiative
Location: San Diego, California, USA
Program Lead: Dr. Jan Karlseder
Focus: Molecular hallmarks of aging with emphasis on genomic stability and nervous system aging.
Key Themes: Neural regeneration, inflammation, longevity pathways.
Homepage: https://www.salk.edu/salk-healthy-aging

Max Planck Institute for Biology of Ageing
Location: Cologne & Munich, Germany
Scientific Directors: Dr. Linda Partridge, Dr. Thomas Langer
Focus: Cross-species molecular and genetic aging mechanisms.
Key Themes: Mitochondrial biology, nutrient sensing, translational longevity research.
Homepage: https://www.age.mpg.de

Albert Einstein College of Medicine – Institute for Aging Research
Location: New York, USA
Director: Prof. Nir Barzilai
Focus: Human longevity genomics and pharmacological prevention.
Key Themes: Centenarian genetics, biomarkers, epigenetics, TAME metformin trial.
Homepage: https://einsteinmed.edu

National Institute on Aging (NIA)
Location: Bethesda/Baltimore, Maryland, USA
Director: Dr. Richard J. Hodes, M.D.
Focus: Federal research leadership across biology, clinical care, social and behavioral aging.
Key Themes: Alzheimer’s, frailty prevention, health disparities, clinical trials.
Homepage: https://www.nia.nih.gov

National University of Singapore – Centre for Healthy Longevity
Location: Singapore
Co-Directors: Prof. Brian K. Kennedy, Prof. Andrea B. Maier
Focus: Preventive and therapeutic clinical interventions for aging.
Key Themes: Biomarkers, clinical trials, healthspan medicine.
Homepage: https://www.lsi.nus.edu.sg/corp/centre-for-healthy-aging

Sheba Medical Center – Healthy Longevity Clinic
Location: Tel HaShomer, Israel
Clinical Lead: Dr. Evelyne Bischof
Focus: Personalized diagnostics and interventions for aging individuals.
Key Themes: AI-driven care, biomarkers, telomere-based medicine.
Homepage: https://www.shebaonline.org

Mayo Clinic – Platform and Longevity Programs
Locations: Rochester, MN; Scottsdale/Phoenix, AZ; Jacksonville, FL
Leadership: Dr. John D. Halamka (President, Mayo Clinic Platform), Dr. Victor M. Montori (DRI Director)
Focus: Digital health strategies and evidence-based personalized care.
Key Themes: Platform integration, minimally disruptive treatment, digital longevity tools.
Homepage: https://www.mayo.edu

Additional Research Institutions

  • USC Leonard Davis School of Gerontology – focus on social determinants of longevity and aging policy.

  • University of Oxford – Institute of Aging – biomarker discovery, metabolomics, cognitive aging.

  • Stanford University Center on Longevity – longevity economics, sustainable policy, lifespan disparities.

  • And there are many more – your Input in this growing HEALTHSPAN WORLD is there fore very much appreciated

Top 25 Leaders in Healthy Longevity Science, Medicine & Healthspan Economy

  1. Dr. Nir Barzilai
    Affiliation: Albert Einstein College of Medicine
    Homepage: einsteinmed.org

  2. Dr. Elizabeth Blackburn
    Affiliation: University of California, San Francisco (UCSF)
    Homepage: ucsf.edu

  3. Dr. Andrew Scott
    Affiliation: Professor of Economics and Finance, London Business School
    Homepage: london.edu

  4. Dr. Brian Kennedy
    Affiliation: National University of Singapore (NUS) & CEO, Buck Institute for Research on Aging
    Homepage: buckinstitute.org

  5. Dr. Andrea B. Maier
    Affiliation: National University of Singapore (NUS), Founding President Healthy Longevity Medicine Society
    Homepage: nus.edu.sg

  6. Dr. Eric Verdin
    Affiliation: CEO, Buck Institute for Research on Aging
    Homepage: buckinstitute.org

  7. Dr. Judith Campisi
    Affiliation: Buck Institute for Research on Aging
    Homepage: buckinstitute.org

  8. Dr. João Pedro de Magalhães
    Affiliation: University of Liverpool
    Homepage: senescence.info

  9. Dr. Vera Gorbunova
    Affiliation: University of Rochester
    Homepage: rochester.edu

  10. Dr. Jan Vijg
    Affiliation: Albert Einstein College of Medicine
    Homepage: einsteinmed.org

  11. Dr. James Kirkland
    Affiliation: Mayo Clinic
    Homepage: mayoclinic.org

  12. Dr. Matt Kaeberlein
    Affiliation: University of Washington
    Homepage: washington.edu

  13. Dr. S. Jay Olshansky
    Affiliation: University of Illinois at Chicago
    Homepage: uic.edu

  14. Dr. Michael West
    Affiliation: AgeX Therapeutics
    Homepage: agexinc.com

  15. Dr. Felipe Sierra
    Affiliation: National Institute on Aging (NIA), NIH
    Homepage: nia.nih.gov

  16. Dr. Ana Maria Cuervo
    Affiliation: Albert Einstein College of Medicine
    Homepage: einsteinmed.org

  17. Dr. David Schneider
    Affiliation: Stanford University
    Homepage: schneiderlab.stanford.edu

  18. Dr. Jeanne Franco
    Affiliation: Buck Institute for Research on Aging
    Homepage: buckinstitute.org

  19. Dr. Aubrey de Grey
    Affiliation: SENS Research Foundation
    Homepage: sens.org

  20. Dr. Maria Blasco
    Affiliation: Spanish National Cancer Research Centre (CNIO)
    Homepage: cnio.es

  21. Dr. Valter Longo
    Affiliation: University of Southern California
    Homepage: gero.usc.edu

  22. Dr. Steve Horvath
    Affiliation: University of California, Los Angeles (UCLA)
    Homepage: horvath.genetics.ucla.edu

  23. Dr. Evelyne Bischof
    Affiliation: Longevity Science Foundation & Human Longevity, Inc.
    Homepage: longevityscience.org

  24. Dr. Leroy Hood
    Affiliation: Buck Institute for Research on Aging
    Homepage: buckinstitute.org

  25. Dr. Satchidananda Panda
    Affiliation: Salk Institute for Biological Studies
    Homepage: salk.edu

And there are so many more excellent and admired Colleagues worldwide we show all our Respect for their Dedication and Work on Healthspan Medicine & Sciences – this is just a starting list as an starting point to connect everybody with some Thought Leadership as Role Models inspiring us all together to generate more knowledge  Healthspan Medicine & Science.

As #HealthyLongevity starts with #HealthyLongevityKnowledge you will find on YouTube and LinkedIn many valuable Resources and Lectures we try to share some on the LinkedIn Page of THE HEALTH CAPTAINS INSTITUTE @ https://www.linkedin.com/company/healthcaptains-institute/

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